Twenty years after a mysterious death rocks Wallace University, another murder takes place.
Auf dem Campus geht ein Mörder um und er hinterlässt keine Spuren nach seinen abscheulichen Taten. Dekanin Munsch gerät ins Schwimmen – die Presse stürmt die Uni und besorgte Eltern rennen ihr die Türe ein. Unterdessen testet die Schwesternschaft neue Bewerberinnen auf Herz und Nieren und Chanel wird von ihrem Freund verlassen …
Chanel hat Hester zu ihrem neuen „Projekt? auserwählt und kümmert sich hingebungsvoll, doch mit strenger Hand um ihren Schützling. Unterdessen entscheidet sich Dekanin Munsch für ein neues Universitäts-Maskottchen und Chad motiviert gemeinsam mit Earl Grey die Verbindungen, den Red Devil zu jagen.
Halloween steht vor der Tür und wie es die Tradition der Schwesternschaft verlangt, ritzen und schnitzen die Damen im Wettbewerb um das kreativste Exemplar fleißig an ihren Kürbissen. Zayday wünschte, sie hätte Kürbis-Sorgen – stattdessen setzt sie panisch einen Notruf ab, denn im Spukhaus „Shady Lane“ spielen sich grauenerregende Dinge ab.
With Halloween just days away, Dean Munsch makes an announcement affecting the campus and, specifically, Chanel's plan to throw a pumpkin patch party in support of her Kappa Kappa Tau presidential campaign. Meanwhile, Grace and Pete lead a search party for a missing friend, which steers them closer to the Red Devil than ever before, and Chanel #3 and #5 learn what life would be like without Chanel.
In an attempt to protect herself from the killer, Chanel makes a surprising decision, which leaves Zayday in a position of power. To stay close to each other, the girls of Kappa Kappa Tau host a slumber party, but when a shocking discovery is made, not everyone will survive the night.
Dean Munsch is left in a desperate situation when a shocking event leads her to come face-to-face with her ex-husband's mistress. Meanwhile, in an attempt to determine who the Red Devil killer is, the Kappas use a Ouija board to communicate with Chanel #2 from beyond the grave and learn of a wicked plot against one of their own.
Grace enlists Chanel’s help to learn more about KKT’s past, and ends up realizing she might not be so different from her nemesis after all. Dean Munsch goes “psycho” when she becomes the latest target of the Red Devils. Meanwhile, Denise becomes the new house mother of Kappa House and a shocking figure from the past returns.
Denise does little to calm the Kappas' fears when she spins a terrifying ghost story. Meanwhile, Hester's shocking announcement pushes Chanel to the edge, and a familiar face returns to campus as the Red Devil claims another victim.
Chad takes Chanel to his family home for Thanksgiving, where she meets his brothers, Brad and Thad, as well as his parents. However, an uninvited guest throws the holiday into chaos. Meanwhile, Dean Munsch gathers the survivors at Kappa House, but dinner quickly explodes into accusations of who among them is really the killer. Then, the Red Devil carves up a deadly main course as another victim falls.
After the horror-filled events of Thanksgiving, the Chanels decide to celebrate their favorite holiday -- Black Friday, but the Red Devil has plans to stop their shopping spree. When the Kappas conclude that Dean Munsch is the killer, they set a plan in motion to stop her once and for all. Meanwhile, Denise lands yet another job, Chad offers Pete a chance to join the Dickie Dollar Scholars and someone confesses to being the murderer.
Shocking confessions are made as the Red Devil is finally unmasked and the killer revealed
Shocking confessions are made as the Red Devil is finally unmasked and the killer revealed.